Columbia Basin Fish and Wildlife Program Columbia Basin Fish and Wildlife Program
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Project Summary

Project 2007-294-00 - Control of BKD by Inactivation of the Renibacterium salmoninarum Sortase Enzyme as an Alternative to Antibiotics
Project Number:
2007-294-00
Title:
Control of BKD by Inactivation of the Renibacterium salmoninarum Sortase Enzyme as an Alternative to Antibiotics
Summary:
This proposal describes research to determine if the sortase gene product of Renibacterium salmoninarum can be a target for therapeutic drugs against Bacterial Kidney Disease of salmon.
Proposer:
None
Proponent Orgs:
National Oceanic and Atmospheric Administration (Govt - Federal)
Starting FY:
2007
Ending FY:
2011
BPA PM:
None
Stage:
Area:
Province Subbasin %
Basinwide - 100.00%
Purpose:
Programmatic
Emphasis:
RM and E
Focal Species:
Species Benefit:
Anadromous: 100.0%   Resident: 0.0%   Wildlife: 0.0%
Tags:
None
Special:
None
BiOp Association:
None

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Review: FY07-09 Solicitation Review

Legal Assessment (In-Lieu)

Assessment Number: 2007-294-00-INLIEU-20090521
Project Number: 2007-294-00
Review: FY07-09 Solicitation Review
Completed Date: 10/6/2006
In Lieu Rating: Problems Exist
Cost Share Rating: None
Comment: Hatchery disease research, other entities (eg hatchery/fishery managers) authorized/required.

Capital Assessment

Assessment Number: 2007-294-00-CAPITAL-20090618
Project Number: 2007-294-00
Review: FY07-09 Solicitation Review
Completed Date: 2/27/2007
Capital Rating: Does Not Qualify for Capital Funding
Capital Asset Category: None
Comment: None

Independent Scientific Review Panel Assessment

Assessment Number: 2007-294-00-ISRP-20060831
Project: 2007-294-00 - Control of BKD by Inactivation of the Renibacterium salmoninarum Sortase Enzyme as an Alternative to Antibiotics
Review: FY07-09 Solicitation Review
Completed Date: 8/31/2006
Final Round ISRP Date: None
Final Round ISRP Rating: Meets Scientific Review Criteria
Final Round ISRP Comment:
This is an excellent proposal, with excellent technical and scientific background. Potential benefits to fish are clear. In reality, many hatchery operations (and the populations they impact) could be affected positively. Project proponents have a good track record of peer reviewed publications and participation in fisheries meetings. Results of the work could have significant and lasting benefits to the artificial production programs, including reducing the impact and risks of these programs to natural fish populations.
Documentation Links:

Council Recommendation

Assessment Number: 2007-294-00-NPCC-20090924
Project: 2007-294-00 - Control of BKD by Inactivation of the Renibacterium salmoninarum Sortase Enzyme as an Alternative to Antibiotics
Review: FY07-09 Solicitation Review
Approved Date: 10/23/2006
Recommendation: Do Not Fund
Comments:

Project Relationships: None